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• Said the Sky (full name Trevor Christensen), American dubstep producer, DJ and musician.
• Sam Devine, a free spirit with epic energy behind the DJ box. In just a few short year’s Sam has blown up on the international scene and quickly emerged as one of dance music’s most influential ladies.
• Sam Paganini, an Italian DJ and producer from Treviso, Veneto, Italy. His 1997 song, "Zoe", made #47 on the UK Singles Chart.
• Sander Kleinenberg born 29 December 1971) is a Dutch disc jockey, VDJ, and record producer.
• Sander van Doorn (real name Sander Ketelaars), Dutch Trance DJ. From the age of sixteen, Van Doorn played two records on turntables. He also experimented with drum computers and making his own productions. This led to a breakthrough as a DJ and producer of dance music.
• Sash! is a German eurodance DJ-producer trio that scored a number of worldwide hits in the late 1990s, the most famous of which are Encore Une Fois and Ecuador.
• Sasha Real name is Alexander Paul Coe (born 4 September 1969), known mononymously as Sasha, is a Welsh DJ and record producer.
• Sebastian Ingrosso (born 20 April 1983) is a Swedish DJ and record producer. He is also a member of the Swedish House Mafia, together with friends Axwell and Steve Angello.
• Sébastien Léger a French house DJ and producer. His singles "Hit Girl", "Hypnotized" and "Aqualight" have become hit dance singles played in clubs across Europe.
• Seth Troxler an American DJ and record producer from Lake Orion, Michigan. His DJ work focuses on house and techno, while he has produced on the labels Wolf + Lamb, Crosstown Rebels and Circus Company, collaborating with artists Art Department, Deetron, Tiefschwarz, Matthew Dear and Subb-an.
• Shanti Celeste the Chilean-born Bristolian was one of the most in-demand DJs of 2015 thanks to her vast vinyl collection, deck skills and most importantly, a genuine love of banging house Bloc, various secret-sundaze and Field Day were highlights.
• Showtek (Sjoerd and Wouter Janssen), Electronic dance music, progressive/electro house.
• Sidney Samson, DJ best known for his Dutch House.
• Skazi, Israeli DJ/producer duo composed of Asher Swissa and Assaf B-Bass, famous for mixing trance with rock music. Swissa began his musical career as a punk rocker in 1990, when he formed a group called Sartan Hashad (en. Breast Cancer) together with three friends.
• Skream Oliver Dene Jones (born 1 June 1986), known as Skream, is an English electronic music producer based in Croydon. Skream was an early and influential exponent of the dubstep genre.
• Skrillex Sonny John Moore (born January 15, 1988), known professionally as Skrillex, is an American DJ, record producer, musician, singer and songwriter.
• Slushii (real name Julian Scanlan), an American electronic dance music producer and DJ.
• Smokin Jo (real name Joanne Joseph) playing style genres include House, techno, deep house the only female to win DJ Magazine's Worlds No 1 DJ award in 1992.
• Solardo is hailing from Manchester, production duo Mark Richards & James Eliot, collectively known as Solardo, are continuing the city’s rich heritage in house music.
• Solomun Mladen Solomun (born December 27, 1975), better known under his stage name Solomun, is a Bosnian-German DJ.
• Sonny Fodera released his first track at the age of 20, Australian born Sonny Fodera has created his own brand of groove driven and emotive house music that resonates with devoted fans around the world.
• Starkillers (real name Nick Terranova).
• Steffi Dutch-born Steffi is a key figure in the realms of contemporary electronic music. A resident at Panorama Bar, and a respected producer and label owner, her work embraces underground electronic culture in its many forms.
• Stephan Bodzin (born 4 August 1969 in Bremen) is a German DJ techno-producer and label owner. Stephan Bodzin also performs as a live artist.
• Steve Angello (full name Steven Angello Josefsson Fragogiannis, born 1982), Greek-born Swedish DJ/producer; former member of the Swedish House Mafia.
• Steve Aoki (born November 30, 1977) is an American DJ, record producer, music programmer, record executive, and heir to his father Rocky Aoki's fortune from the Benihana restaurant franchise.
• Steve Lawler is a British house music producer and DJ born in Birmingham, England. He is a five time DJ Awards winner. Because of his successful performances at Space in Ibiza, he was nicknamed "King of Space".
• Sunnery James & Ryan Marciano a Dutch DJ and producer duo, consisting of Sunnery Gorré and Ryan de Lange.
• Sven Väth Sven Väth (born 26 October 1964) is a German DJ and electronic music producer.
• Swedish House Mafia: Swedish supergroup consisting of Axwell, Steve Angello, and Sebastian Ingrosso. (No longer active).